Pharmacology:Pharmacodynamics:The acyclovirine derivative, which is a synthetic analogue of penicillin antibiotic, has good pharmacodynamic and pharmacovigilance properties. The pharmacology of acyclovirine has been studied in a single dose study onC. canis(noseplaque type 1a ordifficile-related infections),is a gastrointestinal infection,is aChlamydia trachomatis infection(nephrotic syndrome) andChancre infection(nephrotic ulcer). The effect of acyclovirine is mainly antagonized by adenosine. The bioavailability of acyclovirine is approximately 90%. Adenosine is an agonist at the A1/A4 receptor. The bioavailability of the drug is approximately 90%. The A1/A4 receptor is mainly affected by food and is mainly effective when given in high doses. The A4 receptor is mainly affected by food and is mainly effective when given in high doses.

Pharmacokinetics:

Absorption:The usual oral bioavailability of acyclovirine is approximately 90% after a single oral dose. The maximum serum concentration (imalvitretion) is reached within 1-2 days of discontinuing the drug. The AUC of acyclovirine is approximately 4 times higher than that of a placebo. The AUC of acyclovirine after a single oral dose is approximately 2, 3 or 4 times higher than that of a placebo. The CL, CL/48h, AUC and Cmax of acyclovirine are not affected by food. The elimination half-life is 2.5-3.6 hours. The plasma concentration of acyclovirine following the is 80% effective time for the elimination of acyclovirine.

okincomp:

Metabolism:

Protein independent:In a single-dose study, the body weight (AUC), the dose, the route of administration, the volume of distribution and the protein kinetics of acyclovirine have been studied on a daily basis. The steady-state plasma acyclovirine concentrations are achieved within 1-2 days of discontinuing the drug. A single oral dose of acyclovirine (250 mg) was administered to healthy volunteers. Sustained-release (the administration has been studied in the elderly) formulations of acyclovirine have been show to be bioequivalent to zovirax (at a dose of 500 mg) in the form of sustained-release (the administration has been studied in the elderly). Sustanon black is an intravenous route of administration.

Contraindications:

Hypersensitivity;

Hypersensitivity to acyclovirine

Hypersensitivity reactions:Hypersensitivity pneumonitis has been reported. The most common adverse reactions (24%) were headache (12%), myocardial infarction (12%), angina (12%), angioedema (12%), polychondritis (12%) and exocrine-type tumors (12%). In our practice, any patient that does not seek medical attention due to headache and chest pain with acyclovirine, especially if they are over 60 years of age, is at risk for these serious adverse reactions.

Patient Information Panel

Side effects:

The common side effects of acyclovirine include:

More severe reactions

Severe reactions

Liver effects:Liver effects, including jaundice, hepatitis and acute intercurrent hematinuria have been observed in acyclovirine. In the clinical study, the ALT, creatinine and Total bilirubin increased while the AST were not affected in the treatment groups.

Zovirax Cold Sore Cream 2g

Zovirax Cold Sore Cream contains aciclovir, an anti-viral, which penetrates deep into the skin to fight the virus which causes cold sores.

Zovirax contains aciclovir, an anti-viral treatment whichfights the cold sore virus, works at the tingle and blister, speeds healing time and reduces duration of pain.

How to use:

Please read the enclosed leaflet carefully before use.Apply the cream liberally to completely cover the whole of the affected area. Apply to the affected area five times a day at approximately 4 hourly intervals for four days. If your cold sore has not healed after this time, you can use the cream for up to 10 days in total. See the enclosed leaflet for further details. Consult your doctor or pharmacist before using this product if you know that your immune system is weakened.

Hazards and Cautions

If symptoms persist, consult your doctor.Do not exceed the stated dose.Do not use in eyes, on genitals or in the mouth or nose.Do not refrigerate. The ends of the carton have been glued down. Do not use if the carton ends are open.Keep all medicines out of the reach and sight of childrenPrecautionsThis is a medicine; '½ Consult your doctor or pharmacist if you have an underlying medical condition, are taking any other medication or complementary therapy, or if symptoms persist'½ Seek advice before using if you are pregnant, planning to become pregnant, breastfeeding or suffer from allergiesActive ingredients

Ingredients

Active Ingredients:Aciclovir 5% w/wOther ingredients:Dimeticone, Propylene glycol, Poloxamer 407, Cetostearyl Alcohol, Sodium Laurilsulfate, White Soft Paraffin, Liquid Paraffin, Arlacel 165 (Glycol Monostearate, Macrogol Streate 100), Purified Water.

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Experience the swift and effective treatment of cold sores with Zovirax Cream 5%, now available in a convenient 2g tube. Perfect for on-the-go applications, this cream helps to alleviate the symptoms of cold sores, offering relief and promoting faster healing. - Fast-acting formula: Zovirax Cream contains 5% Acyclovir, a potent antiviral medication that targets the herpes simplex virus responsible for cold sores. By applying this cream at the first sign of an outbreak, you can significantly reduce the duration and severity of symptoms. - Easy to use: The cream's smooth consistency allows for easy application without causing further irritation to sensitive areas. Its compact tube size makes it exceptionally portable, ideal for carrying in your purse, car, or even your pocket. - Protective barrier: Besides its antiviral properties, Zovirax Cream helps to soften and protect the affected skin, preventing secondary infections and reducing the likelihood of scarring. Whether you're dealing with frequent outbreaks or the occasional cold sore, Zovirax Cream 5% is an essential tool in your health kit. Keep it handy to ensure you're prepared to tackle cold sores head-on at the very first tingle.

SUNLIFE #1 Online Pharmacy in Qatar, Your one place to order Zovirax Cream 5% - Rapid Relief From Cold Sores In A Handy 2g Tube and All Medicines, Skin Treatment and Anti-viral products. Get delivered in 1 to 2 hours 24/7 FREE Shipping / Home DELIVERY.

AzithromycinDermatitis herpeticum is a skin infection caused by the bacterium Azithromycin, also known as she- servings. This bacterial infection is common in children and is often linked to aging. Azithromycin is an antibiotic that is used to treat bacterial infections of the skin, respiratory, urinary tract, and other parts of the body. Azithromycin may also be prescribed to prevent or treat certain infections, such as acne.AzithromycinAzithromycin is a macrolide antibiotic that belongs to the macrolide family of antibiotics. It is used to treat various bacterial infections, including bronchitis, pneumonia, urinary tract infections, and infections of the skin, ear, brain, and spinal cord. It works by preventing the growth and spread of bacteria. It may also treat some sexually transmitted diseases, such as chlamydia and gonorrhea. DoxycyclineIs a tetracycline antibiotic. Doxycycline is used to treat bacterial infections of the skin, respiratory tract, joints, skin€cm, urinary tract, skin, and soft tissue of animals. Doxycycline is also sometimes prescribed to prevent and treat gastrointestinal infections, such as peptic ulcers. It is also sometimes used to treat rosacea. In the treatment of skin diseases such as psoriasis, ringworm, and dermatitis herpeticus, doxycycline is often used. It works by preventing the bacteria from reproducing and spreading, ultimately stopping the disease from developing. Doxycycline is a tetracycline antibiotic that is used to treat bacterial infections in the body.Is used to treat bacterial infections in the body. In the treatment of acne, minocycline is used. It works by stopping the development of lesions and preventing the further growth of the bacteria. It is used to treat inflammatory acne, which is an acne that develops in rosacea. It is particularly effective against rosacea caused by the type of bacteria that causes rosacea. It works by stopping the production of Propionibacterium acnes, a natural anti-inflammatory that fights bacteria. It is also used to treat inflammatory acne, which is an acne that develops in rosacea.

Zovirax (Acyclovir) Medication Information:

What is Zovirax?

Zovirax is a prescription medicine that belongs to a class of drugs called antivirals. Zovirax contains aciclovir as its active ingredient and has potent antiviral activity. This medication is mainly used for the treatment of viral infections like genital herpes, cold sores, and chickenpox.

Benefits and uses of Zovirax:

• Doctors generally prescribe Zovirax to treat initial episodes of genital herpes and to suppress the frequent recurrence of genital herpes. It is also used to treat herpes labialis (cold sore), herpes zoster (shingles), and chickenpox.
• Zovirax does not cure the viral disease but it reduces your symptoms and the severity of the infection. It helps to decrease pain and itching, speed up sore healing, and prevent new sore formation.
• In people with genital herpes, Zovirax does not protect against the spread of the virus to others. You can spread the virus even if you do not have symptoms. Therefore always use an effective barrier method such as condoms or dental dams during all sexual activity.

How to use Zovirax?

If you are diagnosed with the herpes virus, start the therapy as soon as possible or at the first sign of an outbreak. Your doctor may prescribe you Zovirax tablets depending on your age and medical condition. The tablets are taken orally with or without food.

Recommended dosage:

• For genital herpes:The initial recommended dosage is one 200mg tablet every 4 hours 5 times daily. Use it for no more than 4 days. Consult with your doctor if your symptoms do not improve after 4 days.
• For suppression of recurrent genital herpes:The initial recommended dosage is 200mg three times daily. If conditions do not improve, the dosage can be increased to five times daily.
• For chickenpox:Not more than 800mg 4 times daily for five days. Start the therapy within 24 hours once the rash appears.
• For herpes zoster:800mg of Zovirax every 4 hours, 5 times daily for 7 to 10 days. Start the therapy within 72 hours of the onset of lesions.

Take the medication at the same times every day for maximum benefit. Do not skip any dose, or stop this medication early without consulting your doctor. Always drink enough water while taking Zovirax to prevent the chances of dehydration and kidney damage.

Side effects of Zovirax:

Patients may experience some common side effects after taking Zovirax, including:

• Loss of appetite.
• Diarrhea
• Nausea and Vomiting.
• Stomach pain.
• Headache
• Fatigue
• Fever

Contact your doctor immediately if you notice any serious side effects, including:

• Kidney problems.
• Bloody or dark urine.
• Unusual back pain.
• Agitation, confusion, hallucinations.
• Trouble speaking.
• Sudden vision changes.
• Drug Interactions.

Safety Information:

• Do not take Zovirax if you are allergic to any of its ingredients.
• Before starting the treatment, tell your doctor about your medical history, especially of kidney problems, liver diseases, HIV, and organ transplants.
• Do not use alcoholic beverages or marijuana along with the treatment.
• You should not get certain vaccines including the chickenpox vaccine while using the medication.
• If you are pregnant or a breastfeeding mother, consult with your doctor about the safety of Zovirax.

References:

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Drug Information:

1. Therapy for herpes infections: Acyclovir. URL extracted. PMC chemical formula: COW [immunodeficiency]. Accessed 2024-12-10.
2. Herpesviruses. PMC chemical formula: COC [immunodeficiency].